Untargeted Profiling of Tracer-Derived Metabolites Using Stable Isotopic Labeling and Fast Polarity-Switching LC–ESI-HRMS

[Image: see text] An untargeted metabolomics workflow for the detection of metabolites derived from endogenous or exogenous tracer substances is presented. To this end, a recently developed stable isotope-assisted LC–HRMS-based metabolomics workflow for the global annotation of biological samples ha...

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Publicado en:Anal Chem
Autores principales: Kluger, Bernhard, Bueschl, Christoph, Neumann, Nora, Stückler, Romana, Doppler, Maria, Chassy, Alexander W., Waterhouse, Andrew L., Rechthaler, Justyna, Kampleitner, Niklas, Thallinger, Gerhard G., Adam, Gerhard, Krska, Rudolf, Schuhmacher, Rainer
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2014
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255957/
https://ncbi.nlm.nih.gov/pubmed/25372979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac503290j
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