MCP‐1 downregulates MMP‐9 export via vesicular redistribution to lysosomes in rat portal fibroblasts

Portal fibroblasts (PF) are one of the two primary cell types contributing to the myofibroblast population of the liver and are thus essential to the pathogenesis of liver fibrosis. Monocyte chemoattractant protein‐1 (MCP‐1) is a known profibrogenic chemokine that may be of particular importance in...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Physiol Rep
Päätekijät: Hickman, DaShawn A., Syal, Gaurav, Fausther, Michel, Lavoie, Elise G., Goree, Jessica R., Storrie, Brian, Dranoff, Jonathan A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Wiley Periodicals, Inc. 2014
Aiheet:
Original Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255798/
https://ncbi.nlm.nih.gov/pubmed/25413315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12153
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