Evidence of Convergent Evolution in Humans and Macaques Supports an Adaptive Role for Copy Number Variation of the β-Defensin-2 Gene

β-defensins are a family of important peptides of innate immunity, involved in host defense, immunomodulation, reproduction, and pigmentation. Genes encoding β-defensins show evidence of birth-and-death evolution, adaptation by amino acid sequence changes, and extensive copy number variation (CNV) w...

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Detalhes bibliográficos
Publicado no:Genome Biol Evol
Main Authors: Ottolini, Barbara, Hornsby, Michael J., Abujaber, Razan, MacArthur, Jacqueline A.L., Badge, Richard M., Schwarzacher, Trude, Albertson, Donna G., Bevins, Charles L., Solnick, Jay V., Hollox, Edward J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255768/
https://ncbi.nlm.nih.gov/pubmed/25349268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evu236
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