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Characterization of the complement sensitivity of paroxysmal nocturnal hemoglobinuria erythrocytes.

The affected erythrocytes of paroxysmal nocturnal hemoglobinuria (PNH II and PNH III cells) are abnormally sensitive to complement-mediated lysis. Normal human erythrocytes chemically modified by treatment with 2-amino-ethylisothiouronium bromide (AET) have been used as models for PNH cells inasmuch...

詳細記述

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書誌詳細
出版年:J Clin Invest
主要な著者: Parker, C J, Wiedmer, T, Sims, P J, Rosse, W F
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 1985
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC425569/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4008653/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111927
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