Characterization of the complement sensitivity of paroxysmal nocturnal hemoglobinuria erythrocytes.

The affected erythrocytes of paroxysmal nocturnal hemoglobinuria (PNH II and PNH III cells) are abnormally sensitive to complement-mediated lysis. Normal human erythrocytes chemically modified by treatment with 2-amino-ethylisothiouronium bromide (AET) have been used as models for PNH cells inasmuch...

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Pubblicato in:	J Clin Invest
Autori principali:	Parker, C J, Wiedmer, T, Sims, P J, Rosse, W F
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1985
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC425569/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4008653/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111927
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