Importance of Purity Evaluation and the Potential of Quantitative (1)H NMR as a Purity Assay: Miniperspective

[Image: see text] In any biomedical and chemical context, a truthful description of chemical constitution requires coverage of both structure and purity. This qualification affects all drug molecules, regardless of development stage (early discovery to approved drug) and source (natural product or s...

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Библиографические подробности
Опубликовано в: :J Med Chem
Главные авторы: Pauli, Guido F., Chen, Shao-Nong, Simmler, Charlotte, Lankin, David C., Gödecke, Tanja, Jaki, Birgit U., Friesen, J. Brent, McAlpine, James B., Napolitano, José G.
Формат: Artigo
Язык:Inglês
Опубликовано: American Chemical Society 2014
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255677/
https://ncbi.nlm.nih.gov/pubmed/25295852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm500734a
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