Importance of Purity Evaluation and the Potential of Quantitative (1)H NMR as a Purity Assay: Miniperspective

[Image: see text] In any biomedical and chemical context, a truthful description of chemical constitution requires coverage of both structure and purity. This qualification affects all drug molecules, regardless of development stage (early discovery to approved drug) and source (natural product or s...

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Detalhes bibliográficos
Publicado no:J Med Chem
Main Authors: Pauli, Guido F., Chen, Shao-Nong, Simmler, Charlotte, Lankin, David C., Gödecke, Tanja, Jaki, Birgit U., Friesen, J. Brent, McAlpine, James B., Napolitano, José G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255677/
https://ncbi.nlm.nih.gov/pubmed/25295852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm500734a
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