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Distinct Properties of the Two Isoforms of CDP-Diacylglycerol Synthase

[Image: see text] CDP-diacylglycerol synthases (CDS) are critical enzymes that catalyze the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA). Here we show in vitro that the two isoforms of human CDS, CDS1 and CDS2, show different acyl chain specificities for its lipid substrate....

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Publicado en:Biochemistry
Main Authors: D’Souza, Kenneth, Kim, Yeun Ju, Balla, Tamas, Epand, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2014
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255645/
https://ncbi.nlm.nih.gov/pubmed/25375833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi501250m
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