Mitochondrial CDP-diacylglycerol synthase activity is due to the peripheral protein, TAMM41 and not due to the integral membrane protein, CDP-diacylglycerol synthase 1

CDP diacylglycerol synthase (CDS) catalyses the conversion of phosphatidic acid (PA) to CDP-diacylglycerol, an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol (PI). CDS activity has been identified in mitochondria and endoplasmic reticulum of mam...

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Publicado en:Biochim Biophys Acta
Autores principales: Blunsom, Nicholas J., Gomez-Espinosa, Evelyn, Ashlin, Tim G., Cockcroft, Shamshad
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier Pub. Co 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791848/
https://ncbi.nlm.nih.gov/pubmed/29253589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2017.12.005
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