Low levels of cerebrospinal fluid complement 3 and factor H predict faster cognitive decline in mild cognitive impairment

INTRODUCTION: Alzheimer’s disease (AD) is characterized by the deposition of tau and amyloid in the brain. Although the core cerebrospinal fluid (CSF) AD biomarkers amyloid β peptide 1–42 (Aβ(1–42)), total tau (t-tau) and phosphorylated tau 181 (p-tau(181)) show good diagnostic sensitivity and speci...

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Detalles Bibliográficos
Publicado en:Alzheimers Res Ther
Main Authors: Toledo, Jon B, Korff, Ané, Shaw, Leslie M, Trojanowski, John Q, Zhang, Jing
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255518/
https://ncbi.nlm.nih.gov/pubmed/25478014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/alzrt266
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