CEREBROSPINAL FLUID ABNORMALITIES AND RATE OF DECLINE IN EVERYDAY FUNCTION ACROSS THE DEMENTIA SPECTRUM: NORMAL AGING, MILD COGNITIVE IMPAIRMENT, AND ALZHEIMER’S DISEASE

OBJECTIVES: To investigate the effect of CSF abnormalities on rate of decline in everyday function in normal aging, MCI, and mild AD. DESIGN: T-tau, p-tau(181), and Aβ(42) were immunoassayed in CSF obtained from participants in the AD Neuroimaging Initiative. Random effects regressions were used to...

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Autores principales: Okonkwo, Ozioma C., Alosco, Michael L., Griffith, H. Randall, Mielke, Michelle M., Shaw, Leslie M., Trojanowski, John Q., Tremont, Geoffrey
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888499/
https://ncbi.nlm.nih.gov/pubmed/20558388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archneurol.2010.118
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