Low doses of interferon alpha result in more effective clinical natural killer cell activation.

To define critical parameters concerning interferon (IFN) effects upon natural killer (NK) cells in vivo, we gave cancer patients serial weekly intramuscular injections of purified lymphoblastoid IFN in six doses ranging from 10(5) to 3 X 10(7) U. Dose sequences were determined by randomly allocatin...

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Pubblicato in:	J Clin Invest
Autori principali:	Edwards, B S, Merritt, J A, Fuhlbrigge, R C, Borden, E C
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1985
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC425547/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4008643/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111905
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