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Low doses of interferon alpha result in more effective clinical natural killer cell activation.

To define critical parameters concerning interferon (IFN) effects upon natural killer (NK) cells in vivo, we gave cancer patients serial weekly intramuscular injections of purified lymphoblastoid IFN in six doses ranging from 10(5) to 3 X 10(7) U. Dose sequences were determined by randomly allocatin...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Edwards, B S, Merritt, J A, Fuhlbrigge, R C, Borden, E C
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC425547/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4008643/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111905
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