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Low doses of interferon alpha result in more effective clinical natural killer cell activation.

To define critical parameters concerning interferon (IFN) effects upon natural killer (NK) cells in vivo, we gave cancer patients serial weekly intramuscular injections of purified lymphoblastoid IFN in six doses ranging from 10(5) to 3 X 10(7) U. Dose sequences were determined by randomly allocatin...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Autores principales: Edwards, B S, Merritt, J A, Fuhlbrigge, R C, Borden, E C
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 1985
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC425547/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4008643/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111905
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