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Long non-coding RNA-mediated transcriptional interference of a permease gene confers drug tolerance in fission yeast
Most long non-coding RNAs (lncRNAs) encoded by eukaryotic genomes remain uncharacterized. Here we focus on a set of intergenic lncRNAs in fission yeast. Deleting one of these lncRNAs exhibited a clear phenotype: drug sensitivity. Detailed analyses of the affected locus revealed that transcription of...
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| Publicado en: | Nat Commun |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Pub. Group
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4255232/ https://ncbi.nlm.nih.gov/pubmed/25428589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6576 |
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