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Ligand-Mediated Friction Determines Morphodynamics of Spreading T Cells

Spreading of T cells on antigen presenting cells is a crucial initial step in immune response. Spreading occurs through rapid morphological changes concomitant with the reorganization of surface receptors and of the cytoskeleton. Ligand mobility and frictional coupling of receptors to the cytoskelet...

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Détails bibliographiques
Publié dans:Biophys J
Auteurs principaux: Dillard, Pierre, Varma, Rajat, Sengupta, Kheya, Limozin, Laurent
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255222/
https://ncbi.nlm.nih.gov/pubmed/25468342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.10.044
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