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Ligand-Mediated Friction Determines Morphodynamics of Spreading T Cells

Spreading of T cells on antigen presenting cells is a crucial initial step in immune response. Spreading occurs through rapid morphological changes concomitant with the reorganization of surface receptors and of the cytoskeleton. Ligand mobility and frictional coupling of receptors to the cytoskelet...

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Bibliografiske detaljer
Udgivet i:Biophys J
Main Authors: Dillard, Pierre, Varma, Rajat, Sengupta, Kheya, Limozin, Laurent
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255222/
https://ncbi.nlm.nih.gov/pubmed/25468342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.10.044
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