The yeast polo kinase, Cdc5, regulates the shape of the mitotic nucleus

Abnormal nuclear size and shape are hallmarks of aging and cancer [1, 2]. However, the mechanisms regulating nuclear morphology and nuclear envelope (NE) expansion are poorly understood. In metazoans, the NE disassembles prior to chromosome segregation and reassembles at the end of mitosis [3]. In b...

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Publicat a:Curr Biol
Autors principals: Walters, Alison D., May, Christopher K., Dauster, Emma S., Cinquin, Bertrand P., Smith, Elizabeth A., Robellet, Xavier, D’Amours, Damien, Larabell, Carolyn A., Cohen-Fix, Orna
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255140/
https://ncbi.nlm.nih.gov/pubmed/25454593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2014.10.029
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