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Biochemical evaluation of virtual screening methods reveals a cell-active inhibitor of the cancer-promoting phosphatases of regenerating liver

Computationally supported development of small molecule inhibitors has successfully been applied to protein tyrosine phosphatases in the past, revealing a number of cell-active compounds. Similar approaches have also been used to screen for small molecule inhibitors for the cancer-related phosphatas...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Eur J Med Chem
Hauptverfasser: Hoeger, Birgit, Diether, Maren, Ballester, Pedro J., Köhn, Maja
Format: Artigo
Sprache:Inglês
Veröffentlicht: Editions Scientifiques Elsevier 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255093/
https://ncbi.nlm.nih.gov/pubmed/25159123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2014.08.060
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