Inositol 1,4,5-trisphosphate receptor type II (InsP(3)R-II) is reduced in obese mice, but metabolic homeostasis is preserved in mice lacking InsP(3)R-II

Inositol 1,4,5-trisphosphate receptor type II (InsP(3)R-II) is the most prevalent isoform of the InsP(3)R in hepatocytes and is concentrated under the canalicular membrane, where it plays an important role in bile secretion. We hypothesized that altered calcium (Ca(2+)) signaling may be involved in...

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Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Feriod, Colleen N., Nguyen, Lily, Jurczak, Michael J., Kruglov, Emma A., Nathanson, Michael H., Shulman, Gerald I., Bennett, Anton M., Ehrlich, Barbara E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254986/
https://ncbi.nlm.nih.gov/pubmed/25315698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00236.2014
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