Local pH domains regulate NHE3-mediated Na(+) reabsorption in the renal proximal tubule

The proximal tubule Na(+)/H(+) exchanger 3 (NHE3), located in the apical dense microvilli (brush border), plays a major role in the reabsorption of NaCl and water in the renal proximal tubule. In response to a rise in blood pressure NHE3 redistributes in the plane of the plasma membrane to the base...

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Bibliographic Details
Published in:Am J Physiol Renal Physiol
Main Authors: Brasen, Jens Christian, Burford, James L., McDonough, Alicia A., Holstein-Rathlou, Niels-Henrik, Peti-Peterdi, Janos
Format: Artigo
Language:Inglês
Published: American Physiological Society 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254968/
https://ncbi.nlm.nih.gov/pubmed/25298526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00174.2014
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