Nifedipine increases cholesteryl ester hydrolytic activity in lipid-laden rabbit arterial smooth muscle cells. A possible mechanism for its antiatherogenic effect.

Calcium and cholesterol (CHOL) accumulation are characteristic features of human atherosclerotic plaques. Calcium channel blockers have been shown to increase calcium levels in myocardial cells and suppress free and esterified CHOL deposition in arteries of CHOL-fed animals. To test the hypothesis t...

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Detalles Bibliográficos
Autores principales: Etingin, O R, Hajjar, D P
Formato: Artigo
Lenguaje:Inglês
Publicado: 1985
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC425495/
https://ncbi.nlm.nih.gov/pubmed/3923040
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