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Whole Genome Transcript Profiling of Drug Induced Steatosis in Rats Reveals a Gene Signature Predictive of Outcome

Drug induced steatosis (DIS) is characterised by excess triglyceride accumulation in the form of lipid droplets (LD) in liver cells. To explore mechanisms underlying DIS we interrogated the publically available microarray data from the Japanese Toxicogenomics Project (TGP) to study comprehensively w...

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Pubblicato in:PLoS One
Autori principali: Sahini, Nishika, Selvaraj, Saravanakumar, Borlak, Jürgen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254931/
https://ncbi.nlm.nih.gov/pubmed/25470483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114085
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