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Whole Genome Transcript Profiling of Drug Induced Steatosis in Rats Reveals a Gene Signature Predictive of Outcome

Drug induced steatosis (DIS) is characterised by excess triglyceride accumulation in the form of lipid droplets (LD) in liver cells. To explore mechanisms underlying DIS we interrogated the publically available microarray data from the Japanese Toxicogenomics Project (TGP) to study comprehensively w...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sahini, Nishika, Selvaraj, Saravanakumar, Borlak, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254931/
https://ncbi.nlm.nih.gov/pubmed/25470483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114085
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