Anthrax Lethal Toxin Disrupts the Endothelial Permeability Barrier Through Blocking p38 Signaling

Exposure to anthrax causes life-threatening disease through the action of the toxin produced by the Bacillus anthracis bacteria. Lethal factor (LF), an anthrax toxin component which causes severe vascular leak and edema, is a protease which specifically degrades MAP kinase kinases (MKK). We have rec...

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Bibliographic Details
Published in:J Cell Physiol
Main Authors: LIU, TIEGANG, MILIA, ERICA, WARBURTON, ROD R., HILL, NICHOLAS S., GAESTEL, MATTHIAS, KAYYALI, USAMAH S.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254851/
https://ncbi.nlm.nih.gov/pubmed/21618534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22859
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