Computational and synthetic studies towards improving rescinnamine as an inducer of MSH2-dependent apoptosis in cancer treatment

We, and others, have previously shown that mismatch repair proteins, in addition to their repair function, contribute to cell death initiation. In response to some drugs, this cell death activity is independent of the repair function of the proteins. Rescinnamine, a derivative of the indole alkaloid...

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Библиографические подробности
Опубликовано в: :Mol Cancer Biol
Главные авторы: AbdelHafez, ElShimaa M. N., Diamanduros, Andrew, Negureanu, Lacramioara, Luy, Yan, Bean, J. Hayley, Zielke, Katherine, Crowe, Brittany, Vasilyeva, Aksana, Clodfelter, Jill E., Aly, Omar M., Abuo-Rahma, Gamal El-Din A. A., Scarpinato, Karin D., Salsbury, Freddie R., King, S. Bruce
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254817/
https://ncbi.nlm.nih.gov/pubmed/25485184
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