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The Molecular Origin of the MMR-dependent Apoptosis Pathway from Dynamics Analysis of MutSα-DNA Complexes

The cellular response to DNA damage signaling by MMR proteins is incompletely understood. It is generally accepted that MMR-dependent apoptosis pathway in response to DNA damage detection is independent of MMR's DNA repair function. In this study we investigate correlated motions in response to...

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Detalhes bibliográficos
Main Authors: Negureanu, Lacramioara, Salsbury, Freddie R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389999/
https://ncbi.nlm.nih.gov/pubmed/22712459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07391102.2012.680034
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