Metabolic Dysfunction Consistent with Premature Aging Results from Deletion of Pim Kinases

RATIONALE: The senescent cardiac phenotype is accompanied by changes in mitochondrial function and biogenesis causing impairment in energy provision. The relationship between myocardial senescence and Pim kinases deserves attention since Pim-1 kinase is cardioprotective, in part, by preservation of...

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Vydáno v:Circ Res
Hlavní autoři: Din, Shabana, Konstandin, Mathias H, Johnson, Bevan, Emathinger, Jacqueline, Völkers, Mirko, Toko, Haruhiro, Collins, Brett, Ormachea, Lucy, Samse, Kaitlen, Kubli, Dieter A, De La Torre, Andrea, Kraft, Andrew S, Gustafsson, Asa B, Kelly, Daniel P, Sussman, Mark A
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254755/
https://ncbi.nlm.nih.gov/pubmed/24916111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.115.304441
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