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Fanconi anemia and the development of leukemia

Fanconi anemia (FA) is a rare autosomal recessive cancer-prone inherited bone marrow failure syndrome, due to mutations in 16 genes, whose protein products collaborate in a DNA repair pathway. The major complications are aplastic anemia, acute myeloid leukemia (AML), myelodysplastic syndrome (MDS),...

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Bibliografiske detaljer
Udgivet i:Best Pract Res Clin Haematol
Hovedforfatter: Alter, Blanche P.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254647/
https://ncbi.nlm.nih.gov/pubmed/25455269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.beha.2014.10.002
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