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Immunodeficiency and Immune Dysregulation Associated with Proximal Defects of T Cell Receptor Signaling
Engagement of the T cell receptor (TCR)/CD3 complex triggers a cascade of events that result in T lymphocyte activation and promote positive and negative selection of thymocytes, T lymphocyte migration and effector functions, development and activation of regulatory T cells. Gene mutations that abro...
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| Publicado no: | Curr Opin Immunol |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4254644/ https://ncbi.nlm.nih.gov/pubmed/25459000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2014.10.003 |
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