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7-ketocholesterol accumulates in ocular tissues as a consequence of aging and is present in high levels in drusen

We analyzed by LCMS lipid extracts of lens, retina (MNR) and RPE/Choroid (MPEC) from macaque monkeys 2–25 yr in age to determine their content of 7-ketocholesterol (7KCh) as function of age. In addition we also analyzed drusen capped with retinal pigment epithelium (RPE), RPE, and neural retina from...

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Detalhes bibliográficos
Publicado no:Exp Eye Res
Main Authors: Rodriguez, Ignacio R., Clark, Mark E., Lee, Jung Wha, Curcio, Christine A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254360/
https://ncbi.nlm.nih.gov/pubmed/25261634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2014.09.009
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