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ATP/ADP Ratio, the Missed Connection between Mitochondria and the Warburg Effect

Non-proliferating cells generate the bulk of cellular ATP by fully oxidizing respiratory substrates in mitochondria. Respiratory substrates cross the mitochondrial outer membrane through only one channel, the voltage dependent anion channel (VDAC). Once in the matrix, respiratory substrates are oxid...

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Bibliografiske detaljer
Udgivet i:Mitochondrion
Main Authors: Maldonado, Eduardo N., Lemasters, John J.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254332/
https://ncbi.nlm.nih.gov/pubmed/25229666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2014.09.002
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