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ATP/ADP Turnover and Import of Glycolytic ATP into Mitochondria in Cancer Cells Is Independent of the Adenine Nucleotide Translocator

Non-proliferating cells oxidize respiratory substrates in mitochondria to generate a protonmotive force (Δp) that drives ATP synthesis. The mitochondrial membrane potential (ΔΨ), a component of Δp, drives release of mitochondrial ATP(4−) in exchange for cytosolic ADP(3−) via the electrogenic adenine...

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Vydáno v:J Biol Chem
Hlavní autoři: Maldonado, Eduardo N., DeHart, David N., Patnaik, Jyoti, Klatt, Sandra C., Gooz, Monika Beck, Lemasters, John J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016697/
https://ncbi.nlm.nih.gov/pubmed/27458020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.734814
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