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Involvement of Lysosomal Degradation in VEGF-C–Induced Down-Regulation of VEGFR-3
The vascular endothelial growth factor (VEGF)-C–induced down-regulation of VEGF receptor (VEGFR)-3 is important in lymphangiogenesis. Here, we demonstrate that VEGF-C, -D, and -C156S, but not VEGF-A, down-regulate VEGFR-3. VEGF-C stimulates VEGFR-3 tyrosyl phosphorylation and transient phosphorylati...
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| Publicado en: | FEBS Lett |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4254303/ https://ncbi.nlm.nih.gov/pubmed/25281926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2014.09.034 |
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