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Common features of chromatin in aging and cancer - Cause or Coincidence?

Age is a major risk factor for cancer. Alterations in DNA methylation, histone modifications, chromatin structure and epigenetic regulatory mechanisms are prominent hallmarks of both the aging process and of cancer. Intriguingly – or possibly coincidentally - several chromatin features are common be...

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Detalhes bibliográficos
Publicado no:Trends Cell Biol
Main Authors: Zane, Linda, Sharma, Vivek, Misteli, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254271/
https://ncbi.nlm.nih.gov/pubmed/25103681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2014.07.001
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