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Programmed Hyperphagia secondary to Increased Hypothalamic SIRT1

Small for gestational age (SGA) offspring exhibit reduced hypothalamic neural satiety pathways leading to programmed hyperphagia and adult obesity. Appetite regulatory site, the hypothalamic arcuate nucleus (ARC) contains appetite (NPY/AgRP) and satiety (POMC) neurons. Using in vitro culture of hypo...

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Bibliographic Details
Published in:Brain Res
Main Authors: Desai, Mina, Li, Tie, Han, Guang, Ross, Michael G.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254171/
https://ncbi.nlm.nih.gov/pubmed/25245521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2014.09.031
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