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Fetal Hypothalamic Neuroprogenitor Cell Culture: Preferential Differentiation Paths Induced by Leptin and Insulin

In response to temporally orchestrated growth factor stimulation, developing neural stem/progenitor cells undergo extensive self-renewal and then generate neurons and astrocytes. Fetal neonatal leptin and insulin deficiency results in reduced hypothalamic axonal pathways regulating appetite, which m...

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Detalhes bibliográficos
Main Authors: Desai, Mina, Li, Tie, Ross, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138224/
https://ncbi.nlm.nih.gov/pubmed/21652728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-1217
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