Acute tetrahydrobiopterin supplementation attenuates sympathetic vasoconstrictor responsiveness in resting and contracting skeletal muscle of healthy rats

Tetrahydrobiopterin (BH(4)) is an essential cofactor for the production of nitric oxide (NO) and supplementation with BH(4) improves NO‐dependent vasodilation. NO also reduces sympathetic vasoconstrictor responsiveness in resting and contracting skeletal muscle. Thus, we hypothesized that supplement...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Jendzjowsky, Nicholas G., Just, Timothy P., Jones, Kelvin E., DeLorey, Darren S.
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Periodicals, Inc. 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254091/
https://ncbi.nlm.nih.gov/pubmed/25318748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12164
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