Acute tetrahydrobiopterin supplementation attenuates sympathetic vasoconstrictor responsiveness in resting and contracting skeletal muscle of healthy rats

Tetrahydrobiopterin (BH(4)) is an essential cofactor for the production of nitric oxide (NO) and supplementation with BH(4) improves NO‐dependent vasodilation. NO also reduces sympathetic vasoconstrictor responsiveness in resting and contracting skeletal muscle. Thus, we hypothesized that supplement...

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Publicado en:Physiol Rep
Autores principales: Jendzjowsky, Nicholas G., Just, Timothy P., Jones, Kelvin E., DeLorey, Darren S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Wiley Periodicals, Inc. 2014
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254091/
https://ncbi.nlm.nih.gov/pubmed/25318748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12164
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