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Glutathione Sulfinamide Serves as a Selective, Endogenous Biomarker for Nitroxyl Following Exposure to Therapeutic Levels of Donors

Nitroxyl (HNO) donors exhibit promising pharmacological characteristics for treatment of cardiovascular disorders, cancer and alcoholism. However, whether HNO also serves as an endogenous signaling agent is currently unknown, largely due to the inability to selectively and sensitively detect HNO in...

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Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: Johnson, Gail M., Chozinski, Tyler J., Gallagher, Elyssia S., Aspinwall, Craig A., Miranda, Katrina M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254043/
https://ncbi.nlm.nih.gov/pubmed/25064322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2014.07.022
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