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Glutathione Sulfinamide Serves as a Selective, Endogenous Biomarker for Nitroxyl Following Exposure to Therapeutic Levels of Donors
Nitroxyl (HNO) donors exhibit promising pharmacological characteristics for treatment of cardiovascular disorders, cancer and alcoholism. However, whether HNO also serves as an endogenous signaling agent is currently unknown, largely due to the inability to selectively and sensitively detect HNO in...
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Publicado no: | Free Radic Biol Med |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4254043/ https://ncbi.nlm.nih.gov/pubmed/25064322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2014.07.022 |
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