A genome-wide survey of CD4+ lymphocyte regulatory genetic variants identifies novel asthma genes

BACKGROUND: Genome-wide association studies have yet to identify the majority of genetic variants involved in asthma. We hypothesized that expression quantitative trait locus (eQTL) mapping can identify novel asthma genes by enabling prioritization of putative functional variants for association tes...

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Veröffentlicht in:J Allergy Clin Immunol
Hauptverfasser: Sharma, Sunita, Zhou, Xiaobo, Thibault, Derek M., Himes, Blanca E., Liu, Andy, Szefler, Stanley J., Strunk, Robert, Castro, Mario, Hansel, Nadia N., Diette, Gregory B., Vonakis, Becky M., Adkinson, N. Franklin, Avila, Lydiana, Soto-Quiros, Manuel, Barraza-Villareal, Albino, Lemanske, Robert F., Solway, Julian, Krishnan, Jerry, White, Steven R., Cheadle, Chris, Berger, Alan E., Fan, Jinshui, Boorgula, Meher Preethi, Nicolae, Dan, Gilliland, Frank, Barnes, Kathleen, London, Stephanie J., Martinez, Fernando, Ober, Carole, Celedón, Juan C., Carey, Vincent J., Weiss, Scott T., Raby, Benjamin A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253878/
https://ncbi.nlm.nih.gov/pubmed/24934276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2014.04.011
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