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Nonenzymatic addition of glucocorticoids to lens proteins in steroid-induced cataracts.

A frequent manifestation of long-term glucocorticoid administration is the occurrence of posterior subcapsular cataracts. The molecular basis for this effect has not yet been elucidated. The addition of prednisolone to the rat lens in culture results in a time- and concentration-dependent lens opaci...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Manabe, S, Bucala, R, Cerami, A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC425360/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6501572/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111599
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