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Selective immunotargeting of diabetogenic CD4 T cells by genetically redirected T cells
The key role played by islet-reactive CD8 and CD4 T cells in type 1 diabetes calls for new immunotherapies that target pathogenic T cells in a selective manner. We previously demonstrated that genetically linking the signalling portion of CD3-ζ onto the C-terminus of β(2)-microglobulin and an autoan...
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| Publicado no: | Immunology |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4253509/ https://ncbi.nlm.nih.gov/pubmed/24943731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12340 |
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