Catecholamine exocytosis during low frequency stimulation in mouse adrenal chromaffin cells is primarily asynchronous and controlled by the novel mechanism of Ca(2+) syntilla suppression

Adrenal chromaffin cells (ACCs), stimulated by the splanchnic nerve, generate action potentials (APs) at a frequency near 0.5 Hz in the resting physiological state, at times described as ‘rest and digest’. How such low frequency stimulation in turn elicits sufficient catecholamine exocytosis to set...

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Publicado en:J Physiol
Autores principales: Lefkowitz, Jason J, DeCrescenzo, Valerie, Duan, Kailai, Bellve, Karl D, Fogarty, Kevin E, Walsh, John V, ZhuGe, Ronghua
Formato: Artigo
Lenguaje:Inglês
Publicado: BlackWell Publishing Ltd 2014
Materias:
Molecular and Cellular
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253468/
https://ncbi.nlm.nih.gov/pubmed/25128575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.278127
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