Suppression of Ca(2+) syntillas increases spontaneous exocytosis in mouse adrenal chromaffin cells

A central concept in the physiology of neurosecretion is that a rise in cytosolic [Ca(2+)] in the vicinity of plasmalemmal Ca(2+) channels due to Ca(2+) influx elicits exocytosis. Here, we examine the effect on spontaneous exocytosis of a rise in focal cytosolic [Ca(2+)] in the vicinity of ryanodine...

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Detalhes bibliográficos
Main Authors: Lefkowitz, Jason J., Fogarty, Kevin E., Lifshitz, Lawrence M., Bellve, Karl D., Tuft, Richard A., ZhuGe, Ronghua, Walsh, John V., De Crescenzo, Valerie
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757764/
https://ncbi.nlm.nih.gov/pubmed/19786582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200910285
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