Biphasic regulation of autophagy by miR-96 in prostate cancer cells under hypoxia

Autophagy favors cell survival under hypoxia, and increasing evidence revealed that microRNAs regulate autophagy. We report here hypoxia increased the expression of miR-96 in prostate cancer cells, and miR-96 stimulated autophagy by suppressing MTOR. We found that inhibition of miR-96 abolished hypo...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ma, Yi, Yang, Hao-Zheng, Dong, Bai-Jun, Zou, Han-Bing, Zhou, Yan, Kong, Xian-Ming, Huang, Yi-Ran
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253426/
https://ncbi.nlm.nih.gov/pubmed/25333253
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