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Hypoxia‐responsive miR‐124 and miR‐144 reduce hypoxia‐induced autophagy and enhance radiosensitivity of prostate cancer cells via suppressing PIM1

Cancer cells in hypoxia usually make adaptive changes in cellular metabolism, such as altered autophagy. This might be a cause of enhanced radioresistance in some types of cancer. In this study, we investigated hypoxia‐responsive miRNAs in two prostate cancer cell lines (DU145 and PC3). This study f...

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Vydáno v:Cancer Med
Hlavní autoři: Gu, Hao, Liu, Mingzhu, Ding, Changmao, Wang, Xin, Wang, Rui, Wu, Xinyu, Fan, Ruitai
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924376/
https://ncbi.nlm.nih.gov/pubmed/26990493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.664
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