The class-specific BCR tonic signal modulates lymphomagenesis in a c-myc deregulation transgenic model

Deregulation of c-myc by translocation onto immunoglobulin (Ig) loci can promote B cell malignant proliferations with phenotypes as diverse as acute lymphoid leukemia, Burkitt lymphoma, diffuse large B cell lymphoma, myeloma… The B cell receptor (BCR) normally providing tonic signals for cell surviv...

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Publicat a:Oncotarget
Autors principals: Amin, Rada, Marfak, Abdelghafour, Pangault, Céline, Oblet, Christelle, Chanut, Aurélie, Tarte, Karin, Denizot, Yves, Cogné, Michel
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2014
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253413/
https://ncbi.nlm.nih.gov/pubmed/25229630
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