Glycogen synthase kinase-3β inhibition depletes the population of prostate cancer stem/progenitor-like cells and attenuates metastatic growth

Cancer cells with stem or progenitor properties play a pivotal role in the initiation, recurrence and metastatic potential of solid tumors, including those of the human prostate. Cancer stem cells are generally more resistant to conventional therapies thus requiring the characterization of key pathw...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kroon, Jan, in 't Veld, Lars S., Buijs, Jeroen T., Cheung, Henry, van der Horst, Geertje, van der Pluijm, Gabri
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2013
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253412/
https://ncbi.nlm.nih.gov/pubmed/25344861
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