Glycogen synthase kinase-3β inhibition depletes the population of prostate cancer stem/progenitor-like cells and attenuates metastatic growth

Cancer cells with stem or progenitor properties play a pivotal role in the initiation, recurrence and metastatic potential of solid tumors, including those of the human prostate. Cancer stem cells are generally more resistant to conventional therapies thus requiring the characterization of key pathw...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Kroon, Jan, in 't Veld, Lars S., Buijs, Jeroen T., Cheung, Henry, van der Horst, Geertje, van der Pluijm, Gabri
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2013
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253412/
https://ncbi.nlm.nih.gov/pubmed/25344861
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