Glycogen synthase kinase-3β inhibition depletes the population of prostate cancer stem/progenitor-like cells and attenuates metastatic growth

Cancer cells with stem or progenitor properties play a pivotal role in the initiation, recurrence and metastatic potential of solid tumors, including those of the human prostate. Cancer stem cells are generally more resistant to conventional therapies thus requiring the characterization of key pathw...

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Vydáno v:Oncotarget
Hlavní autoři: Kroon, Jan, in 't Veld, Lars S., Buijs, Jeroen T., Cheung, Henry, van der Horst, Geertje, van der Pluijm, Gabri
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2013
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253412/
https://ncbi.nlm.nih.gov/pubmed/25344861
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