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Downregulation of kinin B1 receptor function by B2 receptor heterodimerization and signaling

Signaling through the G protein-coupled kinin receptors B1 (kB1R) and B2 (kB2R) plays a critical role in inflammatory responses mediated by activation of the kallikrein-kinin system. The kB2R is constitutively expressed and rapidly desensitized in response to agonist whereas kB1R expression is upreg...

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Bibliografske podrobnosti
izdano v:Cell Signal
Main Authors: Zhang, Xianming, Brovkovych, Viktor, Zhang, Yongkang, Tan, Fulong, Skidgel, Randal A.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253050/
https://ncbi.nlm.nih.gov/pubmed/25289859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2014.09.019
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