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Characterization of dual agonists for kinin B1 and B2 receptors and their biased activation of B2 receptors

Kinin B1 and B2 receptors (kB1R and kB2R) play important roles in many physiological and pathological processes. In some cases, kB1R or kB2R activation can have overlapping or complementary beneficial effects, thus an activator of both receptors might be advantageous. We found that replacement of th...

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Detalhes bibliográficos
Main Authors: Zhang, Xianming, Lowry, Jessica L., Brovkovych, Viktor, Skidgel, Randal A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362676/
https://ncbi.nlm.nih.gov/pubmed/22522052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2012.04.002
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